Swine Nutrition and Feed Innovation Team

Research Direction and Topics

Our research areas are focusing on nutritionally modulating sows and gut of piglets. For the nutritional modulation of sows, we mainly study the mechanism of nutritional modulation increasing fetal survival rate in the early gestating sows through endometrial progesterone signaling pathway. For the nutritional modulation of gut of piglets, we mainly study the effects and mechanisms of plant bioactive compounds modulating the gut health of weaned piglets.

Topic 1: Mechanism of nutritional modulation increasing fetal survival rate in the early gestating sows through endometrial progesterone signaling pathway

Through conducting the feeding trials of gestating sows and using modern molecular biological technology, studying the modulation of nutritional level on endometrial progesterone receptor signaling pathway and nutrients (such as amino acid) transport and metabolism; Investigating the target genes directly regulated by progesterone receptor using primary culture of endometrial cells, and then disclosing the regulatory mechanism of progesterone receptor-mediated nutrition level on fetal survival rate.

Topic 2: Effects and mechanisms of plant bioactive compounds modulating the gut health of weaned piglets.

Aiming at the problems of intestinal inflammation and diarrhea in the weaned piglets induced by weaning stress, firstly studying the pathogenic mechanism of post-weaning diarrhea caused by intestinal mucosal inflammation that induced by pathogenic bacteria, and consequently, disclosing the molecular mechanism of plant active compounds reducing inflammatory response and increasing tight junction protein level through regulating the NF-κB pathway.

Team Contact: Xilong LI

Contact Information: 010-62169968; lixilong@caas.cn