研究员 -- 中国农业科学院饲料研究所

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研究员

杨培龙

发布时间：2022-12-20 点击量：【字体：大中小】

杨培龙饲料资源与生物转化创新团队

yangpeilong@caas.cn

1976年出生，理学博士，中共党员，三级研究员，博士生导师。现任中国农业科学院饲料研究所副所长、饲料资源与生物转化创新团队首席。

科研情况

主要从事新型饲料资源和生物转化技术研究，发掘新资源的营养和抗氧化、抗应激功能特性及其饲用价值，建立饲料益生菌及其调控动物生长代谢机制，建立菌虫协同、菌酶协同的资源利用生物转化技术。主持完成“863”、科技成果转化专项、国家科技基础条件平台建设项目、国家转基因生物新品种培育重大专项、科技支撑项目、国家重点研发计划等课题、子课题共10项。作为主要完成人获国家科技进步奖二等奖、北京市科技奖一等奖各1项，获国家专利优秀奖4项，大北农科技奖特等奖1项。授权发明专利86项，发表论文120余篇。

主要成果

1. Hongying Cai, Zhiguo Wen, Xiumei Li, Kun Meng, Peilong Yang∗, Lactobacillus plantarum FRT10 alleviated high-fat diet-induced obesity in mice through regulating PPARα signal pathway and gut microbiota. Applied Microbiology and Biotechnology 2020, 104(13):5959-5972.

2. Hongying Cai, Zhiguo Wen, Kun Meng, Peilong Yang∗. Metabolomic signatures for liver tissue and cecum contents in high-fat diet-induced obese mice based on UHPLC-Q-TOF/MS. Nutrition & Metabolism 2021, 18(1):69.

3. Hongying Cai, Zhiguo Wen, Xin Xu, Jiaxin Wang, Xuan Li, Kun Meng, Peilong Yang∗. Serum metabolomics analysis for biomarker of Lactobacillus plantarum FRT4 in high-fat diet-induced obese mice. Foods 2022, 11(2):184.

4. Hongying Cai, Zhiguo Wen, Kun Meng, Peilong Yang∗. Lactobacillus plantarum FRT4 alleviated obesity by modulating gut microbiota and liver metabolome in high-fat diet-induced obese mice. Food & Nutrition Research 2022, 66:7974.

5. Hongying Cai, Zhiguo Wen; Daojie Li; Yunsheng Han; Kun Meng; Peilong Yang*. Metabolomic Characteristics of Liver and Cecum Contents in High-Fat-Diet-Induced Obese Mice Intervened with Lactobacillus plantarum FRT10. Foods, 2022, 11, 2491.

6. Lulu Zhao, Hongying Cai, Yongbao Wu, Changfu Tian, Zhiguo Wen, Peilong Yang*. Severe choline deficiency induces alternative splicing aberrance in optimized duck primary hepatocyte cultures. Animal Bioscience 2022, 35(11):1787-1799.

7. Jing Liu, Lulu Zhao, Hongying Cai, Zitao Zhao, Yongbao Wu, Zhiguo Wen, Peilong Yang*. Antioxidant and Anti-Inflammatory Properties of Rubber Seed Oil in Lipopolysaccharide-Induced RAW 267.4 Macrophages. Nutrients 2022, 14(7):1349.

8. Wei Luo, Jinglong Xu, Huiying Chen, Huili Zhang, Peilong Yang*, Xiaobin Yu. Synthesis of L-asparagine Catalyzed by a Novel Asparagine Synthase Coupled With an ATP Regeneration System. Frontiers in Bioengeering and Biotechnology 2021, 9:747404.

9. Zhiguo Wen, Yongbao Wu, Zhiguo Qi , Xiumei Li , Fuhuang Li, Xuezhuang Wu, Peilong Yang. Rubber seed oil supplementation enriches n-3 polyunsaturated fatty acids and reduces cholesterol contents of egg yolks in laying hens. Food Chemistry 2019, 301:125198.

10. Phytase variants YeAPPA having improved gastric protein resistance and acid resistance, and increased catalytic efficiency，2021年，美国US 11,155,793 B2

11. Phytase variants YkAPPA having improved pepsin resistance and increased catalytic efficiency，2021年，美国US 11,028,377 B2

12. α-半乳糖苷酶突变体Gal27B-A16及其编码基因和应用，ZL201810033238.2

13. 植酸酶突变体YkAPPA-L327V、YeAPPA-L327V及其编码基因和应用，ZL 201610527413.4

14. 植酸酶突变体YkAPPA-L396V、YeAPPA-L396V及其编码基因和应用，ZL 201610527405.X